Cancer Glossary - #

10-propargyl-10-deazaaminopterin   A substance that is being studied as an anticancer drug. It belongs to the family of drugs called folate analogues.

12-O-tetradecanoylphorbol-13-acetate   TPA. A drug that is being studied as a treatment for hematologic cancer.

13-cis retinoic acid   A drug that belongs to the family of drugs called retinoids. It is used in the treatment of acne and psoriasis and is being studied in cancer prevention. Also called isotretinoin.

17-N-allylamino-17-demethoxy geldanamycin   A substance that is being studied as an anticancer drug. It belongs to the family of drugs called antitumor antibiotics.

1H-nuclear magnetic resonance spectroscopic imaging   A noninvasive imaging method of detecting and measuring activity at the cellular level. It provides chemical information and is used in conjunction with magnetic resonance imaging (MRI), which gives spatial information. Also called proton magnetic resonance spectroscopic imaging.

2-methoxyestradiol   2ME2. A drug derived from estrogen that belongs to the family of drugs called angiogenesis inhibitors. It prevents the formation of new blood vessels that tumors need in order to grow.

2IT-BAD monoclonal antibody 170   A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells.

3-aminopyridine-2-carboxaldehyde thiosemicarbazone   3-AP. A substance that is being studied as an anticancer drug. It belongs to the family of drugs called ribonucleotide reductase inhibitors.

3-AP   3-aminopyridine-2-carboxaldehyde thiosemicarbazone. A substance that is being studied as an anticancer drug. It belongs to the family of drugs called ribonucleotide reductase inhibitors.

3-D   3-dimensional. A graphic display of depth, width, and height.

3-dimensional   3-D. A graphic display of depth, width, and height.

3-dimensional radiation therapy   A procedure that uses computers to create a 3-dimensional picture of the tumor. This allows doctors to give the highest possible dose of radiation to the tumor, while sparing the normal tissue as much as possible.

4'-iodo-4'-deoxydoxorubicin   An anticancer drug that belongs to the family of drugs called antineoplastic antibiotics.

4-demethoxydaunorubicin   An anticancer drug that belongs to the family of drugs called antitumor antibiotics. Also called idarubicin.

5-FU   An anticancer drug that belongs to the family of drugs called antimetabolites. Also called fluorouracil.

5-hydroxyindoleacetic acid   5HIAA. A breakdown product of serotonin that is excreted in the urine. Serotonin is a hormone found at high levels in many body tissues. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be measured in the urine to test for carcinoid tumors.

506U78   An anticancer drug that belongs to the family of drugs called antimetabolites.

6-hydroxymethylacylfulvene   An anticancer drug that belongs to the family of drugs called alkylating agents. Also called irofulven.

9-cis retinoic acid   A drug being studied for cancer prevention. It belongs to the family of drugs called retinoids.

90Y-DOTA-biotin   A radioactive substance (yttrium-90) joined by a large chemical link (DOTA) to biotin, a vitamin.