The hallmark symptoms of the
disorder are dry mouth and dry eyes. In addition, Sjogren's syndrome
may cause skin, nose, and vaginal dryness, and may affect other
organs of the body including the kidneys, blood vessels, lungs,
liver, pancreas, and brain.
There is no known cure for Sjogren's syndrome nor is there a
specific treatment to restore gland secretion. Treatment is
generally symptomatic and supportive. Moisture replacement therapies
may ease the symptoms of dryness. Nonsteroidal anti-inflammatory
drugs may be used to treat musculoskeletal symptoms. For individuals
with severe complications, corticosteroids or immunosuppressive
drugs may be prescribed.
Sjogren's can damage vital organs of the body with symptoms that
may plateau, worsen, or go into remission. Some people may
experience only the mild symptoms of dry eyes and mouth, while
others go through cycles of good health followed by severe
Many patients are able to treat
problems symptomatically. Others are forced to cope with blurred
vision, constant eye discomfort, recurrent mouth infections, swollen
parotid glands, hoarseness, and difficulty in swallowing and eating.
Debilitating fatigue and joint pain can seriously impair quality of